지속성 빈혈 고양이의 전구체 표적 면역매개성 빈혈(PIMA) 진단

1세 Scottish Fold 고양이의 6개월 지속 빈혈에서 면역억제 치료에 불충분한 반응을 보임. 골수 검사에서 적혈구계 과형성(M:E 0.35:1) 확인 후 클로람부실로 전환하여 15개월간 안정 관리. PIMA 의심 진단 사례.

The immune-mediated destruction of erythroid precursors within the Hyeona Bae bone marrow can result in inefficient erythropoiesis, classified as precursor-tarDoHyeon Yu* geted immune-mediated anemia (PIMA). Herein, we describe the case of a 1-year-old Scottish Fold cat who presented with a pale mucous membrane with College of Veterinary Medicine, a history of prior diagnosis with immune-mediated hemolytic anemia (IMHA), Gyeongsang National University, Jinju characterized by normocytic normochromic moderate anemia. The cat was ad- 52828, Korea ministered six months of immunosuppressive therapy, including prednisolone, cyclosporine, or mycophenolate mofetil, but exhibited insufficient reticulocytosis. Bone marrow examination subsequently revealed a decreased myeloid to erythroid ratio of 0.35:1, and PIMA was diagnosed. Treatment modification with chlorambucil was implemented, and the cat remained well-managed without IMHA recurrence for 15 months. This case highlights the importance of careful evaluation methods, such as reviewing medication history and performing bone marrow examinations, in IMHA patients with an insufficient response to immunosuppressive therapy. These results further suggest the occasional need for medication adjustments during treatment.